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It means either the dose is wrong, the compound doesnt work for you, the product quality is poor, or the effect size is below what you can detect subjectively

Its antioxidant properties also protect against environmental damage that can lead to premature ageing and dullness

Lee, S., Doxey, A

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Kuhlman, B

Aberrant activation of ferroptosis pathways is a hallmark of various pathologies, such as malignancies and chronic inflammatory disorders