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Chemoprevention of pancreatic cancer using solid-lipid nanoparticulate delivery of a novel aspirin, curcumin and sulforaphane drug combination regimen

Various technologies such as whole genome and exome sequencing, bulk RNA-seqencing (RNA-seq) and single-cell RNA-seq analyses utilizing next-generation sequencing technology, have been employed to screen for genomic mutations and assess their functional consequences

A further strategy is to hit key metabolic transformations that occur in cancer cells, whereby the metabolic adaptations to hypoxic conditions seem to be specific for cancer cells, shared in many tumor types and required for neoplastic growth

Control of oxygen tension recapitulates zone-specific functions in human liver microphysiology systems

He returned to Broadway in the Tony Award-winning The Play That Goes Wrong and appeared as Aaron Burr in the Chicago cast of Hamilton

Modification of particular residues resulting in an increase of peptide charge and basic residues on the polar face of the molecule compared to a neutral wild-type peptide, enhanced the antibacterial activity of peptides derived from the cecropin D-like natural sequence