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AFs cause a wide range of morbidities ranging from acute toxicity, biliary atresia to massive hepatic necrosis, kidney injury, protracted genotoxicity, mutagenicity, carcinogenicity, and mortality

Mutations in the dopamine receptor genes, especially DRD1 and DRD2, are also associated with the development of neuropsychiatric and neurological diseases, given that a mutation can lead to the disruption of the signaling through changes in the synthesis, storage, and release of dopamine (Cabana-Dominguez et al., 2022

By contrast, machine learning methods such as the generalized linear model, support vector regression and random forest regression compensated for these differences and predicted the global target values much more accurately (Fig

Clin Chem 44 : 825832 Robinson BH, Glerum DM, Chow W, Petrova-Benedict R, Lightowlers R, Capaldi R 1990 The use of skin fibroblast cultures in the detection of respiratory chain defects in patients with lacticacidemia

Flam BR, Eichler DC, Solomonson LP

A more recent Danish study in COPD patients with hypertension among 1.3 million people showed that treatment with -blockers reduced COPD hospitalization and mortality more than any other antihypertensive drug 111