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FIGURE 2 3.2 NNMT and diabetes Diabetes is caused by a fundamental disturbance in the metabolism of glucose and is characterised by IGT, elevated fasting blood glucose, and inadequate insulin secretion or IR (Tripathi and Srivastava, 2006

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Evaluation of: Glycerol production (a marker of lipolysis) 2-deoxyglucose uptake (a marker of insulin signaling) DNA synthesis (a marker of proliferation) What they found: AOD-9604 stimulated lipolysis dose-dependently from 10 M, with a plateau at 10 M Full hGH stimulated lipolysis to a similar maximum, but with different kinetics AOD-9604 did not affect glucose uptake or DNA synthesis at all, whereas hGH inhibited both (the classic lipotoxic GH effect) Fragments with different sequence (from the N-terminal part of hGH) had no lipolytic effect Why it matters: This was the first publication of AOD-9604

Opposite directions in the GH biology pathway

All findings described here are from controlled preclinical research settings

Quick Reference INCI Name: Copper Tripeptide-3 Common Names: AHK-Cu, copper peptide for hair Category: Peptide, signal peptide Source: Synthetic (laboratory created) Nubeean Concentration: 1% Carrier System: Aqueous serum base with MSM for absorption support Suited To: Those seeking to support scalp health and hair vitality Cautions: Store in a cool, dark place