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For instance, a trial of an IL-6 inhibitor could target patients identified as having a high IL-6 genotype or high pre-op IL-6 levels, to enrich for those likely to benefit

doi: 10.1158/2159-8290.CD-22-0750 93 ZhuoSChenZYangYZhangJTangJYangK

doi: 10.1016/j.cell.2011.02.013 46 NunesSCRamosCSantosIMendesCSilvaFVicenteJBet al

Biol Open 8(2):bio037655 Coca-Pelaz A, Shah JP, Hernandez-Prera JC, Ghossein RA, Rodrigo JP, Hartl DM, Olsen KD, Shaha AR, Zafereo M, Suarez C (2020) Papillary thyroid canceraggressive variants and impact on management: a narrative review

Most American diets, if varied, provide enough B vitamins, although some people may need to supplement choline and vitamin B6

Colman, R