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Zhang C, Xie Y, Chen H, Lv L, Yao J, Zhang M, Xia K, Feng X, Li Y, Liang X, Sun X, Deng C, Liu G

Caspase-3 activity was quantified in nanomoles of 7-Amino-4-methylcoumarin (the fluorescent product) liberated from acetyl-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin per minute per milliliter of cell lysate, calculated using the formula: Where v = volume of the sample in milliliters, d = dilution factor, and t = reaction time in min

Studies were excluded if they were deemed unrelated to the topics of interest, published in a language other than English, and focused on children with syndromic/genetic disorders

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