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Postoperative delirium is associated with increased plasma neurofilament light

This review integrates mechanistic insights with translational advances, outlining how dysregulation of chaperones, autophagy-mitophagy, the ubiquitinproteasome system, and ER stress pathways drive human diseases, while highlighting emerging therapeutic platforms, from pharmacological chaperones and autophagy modulators to targeted protein degradation technologies, CRISPR screens, spatial biology, and AI-guided drug discovery

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Genetic mutations in FKS1 gene associated with acquired echinocandin resistance in Candida parapsilosis complex

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