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Fundamentally, the premature downregulation of the expression of growth control TFs, particularly hairy and enhancer of split-1 (HES1) in fibroblasts and Krppel-like factor 6 (KLF6) in basal cells, underlies the distinct transcriptional alterations occurring at the cellular level

For the positive tumor control, MDA-MB-231 cells seeded onto sterile glass slides were cultured until confluent, and then transferred onto the egg yolk

Tobin NP, Sims AH, Lundgren KL, Lehn S, Landberg G

-Gal A missense variants associated with Fabry disease can lead to ER stress and induction of the unfolded protein response

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Smoking, antipsychotic metabolic effects, inflammation, poor diet, substance use and copper-zinc imbalance may increase mitochondrial stress