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MOTS-c & Anti-Aging Research Modern aging research is increasingly focused on: Mitochondrial dysfunction Inflammaging Oxidative stress Cellular resilience Metabolic decline MOTS-c intersects with several hallmarks of aging: Loss of mitochondrial efficiency Chronic inflammation Metabolic dysfunction Reduced stress adaptation Muscle decline Researchers are studying whether mitochondrial peptides may someday become part of: Preventive longevity medicine Healthy aging strategies Regenerative wellness protocols MOTS-c, Inflammation & Inflammaging One of the biggest drivers of aging today is chronic low-grade inflammation

doi: 10.3389/fimmu.2025.1550724 Received 23 December 2024 Accepted 05 March 2025 Published 24 March 2025 Volume 16 - 2025 Edited by Daniel P Potaczek, University of Marburg, Germany Reviewed by Tarek A

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