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[DOI] [PubMed] [Google Scholar] 231.Harris AL

However, there are some things to keep in mind: Allergic Reactions: May be seen rarely in sensitive individuals

Yes, continuous, long-term administration can lead to pituitary receptor desensitization, reducing the effectiveness of the peptides

Alternatively, one might imagine that, if an ancestral metazoan evolved a TGR enzyme that could replace both the ancestral TrxR and Gsr activities, as the version does, then perhaps the ancestral type TrxR and the ancestral Gsr were simply and irrevocably lost as being redundant with the new bi-functional TGR enzyme, as seen in

Dai, Q., Walkey, C

Cautious and steady progress is always better than looking for a "miracle" that promises instant results but lacks the science to back it up