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Description

Recent studies identified a novel copper-dependent form of cell death called cuproptosis, which is distinct from all other known pathways underlying cell death

as the most potently reactive ROS species damages DNA by causing OH

These range from the idea that aging is due to wear and tear and an accumulation of damage with the passage of time to more specific concepts of preprogrammed life span defined by specific age-related genes

Results vary by peptide and individual response patterns

(2013) Biochimica et Biophysica Acta | Li J

Consequently, the concept of utilizing Pt nanozymes to modulate cellular ROS, intervene in the immune response, metabolism, and other ROS-related signaling pathways, and thereby manipulate cellular redox homeostasis has stimulated a global surge in research activity