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Goldstein, MD, is a professor and holds the Catharine B

When the peptide activates or modulates these receptors, it triggers intracellular signaling involving cAMP elevation, protein kinase A activation, and hormone-sensitive lipase stimulation, ultimately leading to triglyceride breakdown and fat mobilization

It appears that age-related organ dysfunction and age-related diseases are, at least in part, governed by impairment in tissue energy metabolism [1-14]

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Prescribers must recognize this possibility and educate patients on these effects