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Betaine also demonstrates antioxidant and anti-inflammatory activities and has a promising therapeutic value in several human diseases, including homocystinuria and fatty liver disease

Elevated plasma TMAO concentrations predict incident CVD risks in multiple clinical cohorts (47, 914), and both animal models with microbial transplantation (4, 15) and various studies on mice and humans with raised TMAO have revealed mechanistic and prognostic links between microbial TMAO production and both atherosclerosis and thrombosis, as well as chronic kidney disease and heart failure (46, 12, 13, 1618)

Renowned for its rapid, high-throughput analytical capabilities, this method maintains sample integrity without the need for auxiliary gases

Deep sleep is believed to be important for tissue regeneration and repair, as well as metabolic and immune regulation, hormone balance, and memory

Also, high levels were associated with worse outcomes in people with primary sclerosing cholangitis, an immune-related disease of the liver [34]