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the phrase low tolerance refers to a state in which the patient suffers from side effects from treatment so that the patient does not benefit from and/or will not continue therapy because of the adverse effects and/or the harm from the side effects outweighs the benefit of the treatment

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Supports healthy liver function by improving protein, enzyme, and bilirubin levels in the blood

It is not surprising that EtPhCbl and PhEtyCbl both exhibit diculty in dissociating the upper axial ligand as these cobalamins have been shown to be metabolically inert