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For others, it can take a few weeks to notice big changes

With more beta-3 adrenergic receptors present on the surface of adipocytes (fat cells), the cells may become more sensitive to lipolytic signals

However, talk to your treating doctor if any of the side effects continue

Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy