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Without moderation and a healthy balanced diet, people that drink large amounts of alcohol can become vitamin B12 deficient

A single exposure of doxorubicin between 0 and 50 M, yields minimal cytosolic GSH depletion (2.5% maximum decrease), which recovers within the prescribed time-span (Fig

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Similarly, it is suspected that the very low-protein content and low availability of the amino acid methionine may also be a direct contributor to the development of fatty liver

Front Integrative Neurosci 13:48 Li X, Zhu Q, Wang Q, Zhang Q, Zheng Y, Wang L, Jin Q (2020) Protection of sacubitril/valsartan against pathological cardiac remodeling by inhibiting the NLRP3 inflammasome after relief of pressure overload in mice

The absence of safety data in these populations means that use should be avoided or approached with extreme caution and specialized medical supervision