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Figure 1 Autoimmune mechanisms have also been implicated in the pathogenesis of HIVAC through HIV-induced B-cell stimulation leading to autoantibody production directed against the myocardium ( 3 Clinical manifestations and diagnosis 3.1 Signs and symptoms Like other forms of cardiomyopathy, peripheral edema, involving the legs, ankles, feet, or abdomen, frequently results from fluid retention secondary to compromised myocardial function

10.1371/journal.ppat.1009942 [DOI] [PMC free article] [PubMed] [Google Scholar] 404

Without baseline biomarker assessmentsuch as serum B12, homocysteine, or liver function markersit is difficult to determine whether deficiency in any component is limiting your metabolic capacity or whether supplementation will meaningfully improve outcomes

Both intramuscular and intragastric administration significantly reduce ulcer area and accelerate healing across different experimental models

clinical corroboration is needed