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When aging and oxidative stress diminish CMA activity, protein damage intensifies, leading to increased aggregation and elevated oxidation levels (90)

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doi: 10.3390/ijms22020764 36 ReiterRJTanDXOsunaCGittoE

Pathological consequences start occurring when an excess of synaptic zinc leaks in to the post synaptic neurons through the ion channels (Sensi et al., 2011)

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