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Often, elder siblings, friends or fianc/fiance/spouse lack an in-depth knowledge on cosmetics and provide their recommendation based on their experience, which could be the underlying reason for this observation (40)

The ENS communicates with the autonomic nervous system (ANS) and CNS through sensory and motor neurons as well as neurotransmitters

It has been demonstrated that dendritic cells downregulate CD80 expression, preventing T cell activation via CD28, and exhibit high amounts of PD-L1

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Liposomal encapsulation significantly enhanced transdermal delivery and barrier recovery, suggesting potential benefits in terms of stability, permeability, and immune modulation (Kim et al., 2015)