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Exercise-Induced Oxidative Stress Intense or prolonged exercise generates substantial oxidative stress through increased oxygen consumption and metabolic rate, increased mitochondrial electron leakage producing reactive oxygen species, recruitment of inflammatory immune cells to exercising muscles, and mechanical stress on tissues producing oxidative damage

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Verma S, Verma PK, Meher AK, Bansiwal AK, Tripathi RD, Chakrabarty D (2018) A novel fungal arsenic methyltransferase, WaarsM reduces grainarsenic accumulation in transgenic rice ( Oryza sativa L.)

Combining pulldown experiments and functional assays to identify senolytic targets To identify the targets responsible for their senolytic activity, we synthesized two alkynylated derivatives of each compound, which we used to perform target identification in competitive, protein-directed activity-based protein profiling (ABPP) experiments (Fig