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Conclusions In this study, 16S rRNA sequencing, metabolomics, metabolite traceability, and molecular docking techniques were integrated to demonstrate that there was a cross-talk between gastric mucosal microbes and mitochondria

The glomerular pattern is excretion of high-molecular-weight proteins, such as IgG, and indicates increased permeability or decreased selectivity of the glomerular barrier

Yes, but the combination requires caution

We further demonstrated that an increase in urinary GSH concentrations during the formation of TLS is a common phenomenon in both mice and humans and proposed the utility of urinary GSH as a biomarker to detect TLS in the kidney

Hypoxia and oxidative stress in breast cancer

Among tyrosine kinase inhibitors, imatinib (a PDGFR inhibitor) and erlotinib (an EGFR inhibitor) induce ROS-dependent apoptosis in melanoma and non-small-cell lung cancer cells, respectively, through disruption of mitochondrial membrane potential upon the stimulation of JNK and p38 phosphorylation 88,89 , while vemurafenib (a BRAF inhibitor) increases the production of superoxide anions with the commensurate depolarization of the mitochondrial membranes in melanoma cells 90