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The most common is an initial shedding phase in the first four to eight weeks of use, when follicles in late telogen are pushed into a new cycle and shed simultaneously before new growth begins

Deficiency can also lead to neurological symptoms such as numbness or tingling in the hands and feet, difficulty walking, memory problems, and depression

Serious but less common risks may include: hypersensitivity reactions, hypokalemia (rare, with B12 correction of severe deficiency), and exacerbation of polycythemia

One of the jobs of B12 is to help produce healthy red blood cells, which carry oxygen throughout your body