DBCO-Dap(m-PEG4)-Val-Cit-PAB deuterium-labeled-ketone Nature Chem 5

Nature Chem 5

571 Purity (HPLC) >= 95% Solubility DMSO

enabling efficient and selective conjugation of the payload to the linker

Product Name: Cy3 azide trisulfo Synonyms: Cy3 azide

697 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCCOCC#C)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DBCO-Dap(m-PEG4)-Val-Cit-PAB deuterium-labeled-ketone Nature Chem 5SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG,