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Eur J Pharmacol 667(1-3):322329 B Klicek R, Kolenc D, Suran J et al (2013) Stable gastric pentadecapeptide BPC 157 heals cysteamine-colitis and colon-colon-anastomosis and counteracts cuprizone brain injuries and motor disability

BPC-157 (Body Protection Compound-157) es un pentadecapptido sinttico derivado de una protena gstrica, ampliamente utilizado en estudios sobre citoproteccin, angiognesis y procesos de reparacin tisular en modelos preclnicos

For short-term storage, standard refrigeration (2C to 8C) is acceptable

In tolerance assay, at 42 h after the end of conditioning regimen, shorter preconvulsive latencies than in healthy (non-diazepam conditioned) mice following isoniazid (800 mg/kg i.p.) (as hallmark of tolerance) were observed if diazepam (5.0 mg/kg i.p.) was again given acutely to mice previously conditioned with diazepam alone (use of picrotoxin 3.0 mg/kg i.p., as convulsant, with acute application of diazepam in previously diazepam conditioned mice did not lead to tolerance hallmark)