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Isatuximab plus pomalidomide and dexamethasone in patients with relapsed/refractory multiple myeloma according to prior lines of treatment and refractory status: ICARIA-MM subgroup analysis

Originally conceived to replicate the fat-metabolising action of hGH without its broader endocrine effects, it was once viewed as a promising metabolic research molecule

5-Amino-1MQ inhibits the enzyme NNMT (nicotinamide N-methyltransferase), which preserves intracellular NAD+ and activates AMPK-dependent mitochondrial fat oxidation

Six controlled trials in approximately 900 participants are summarized in Stier et al

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