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These active components may offer new therapeutic approaches for improving ovarian reserve by regulating endocrine functions, providing antioxidant effects, and inhibiting apoptosis (Fig

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Interleukin-13 IL-13 is a modulator of dopaminergic neuron survival through its receptor IL13RA1, which is expressed in the SNpc and ventral tegmental area of the brain [211]

Given its ease of access as an over-the-counter medication, the United States Food and Drug Administration had stated it is safe to consume up to a maximum dose of 4000 mg within 24 h[6,7] while experts recommend a dose of 2000 mg or less in patients with existing liver disease or with chronic alcohol use[8-10]

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