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This makes the combination particularly well suited to mechanistic studies of receptor cross-talk, signal amplification, and pulse generation that single-receptor models cannot adequately replicate [2][3]

Wan M, Ding L, Wang D, Han J, Gao P (2020) Serotonin: a potent immune cell modulator in autoimmune diseases

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Notably, key molecular pathways involved in these effects include Nrf2/HO-1, NF-B, NLRP3/Caspase-1, JNK/c-Jun/AP-1, PPAR/FSP1 and Akt/GSK-3/-catenin

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