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These results, in line with our previous in vitro and ex vivo results, confirm the therapeutic capacity of dyclonine and leucovorin to promote oligodendrogenesis in a model of preterm birth brain injury and validate the intranasal approach to administer these compounds and their capacity to cross the blood-brain barrier (BBB)

The study compared two groups of women where one group received 600 mg NAC and 500 mcg folic acid daily, and the other group only received NAC

Curr Drug Targets 7(6):661668 Park MH, Hong JT (2016) Roles of NF-B in cancer and inflammatory diseases and their therapeutic approaches

In transgenic AD models, exercise decreases pro-inflammatory cytokine expression, diminishes amyloid burden, and improves spatial learning (Mielke et al., 2025)

PTEN S-nitrosylation by NOS1 inhibits autophagy in NPC cells