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We found no significant correlation between changes in the IRLS and MIDAS scores before and 3 months after CGRP mAb treatment, and 66.6% of nonresponders who did not achieve a 50% reduction in the number of MMDs after 3 months presented at least some improvement in RLS symptoms

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It is important to note that most of the studies that showed decreased superoxide production in response to G6PD inhibition did not examine the balance between decreased superoxide production and GSH capacity

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