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This disruption leads to dysregulated mitochondrial biogenesis and metabolism, as well as decreased antioxidant activity of mitochondrial superoxide dismutase (SOD2), which converts superoxide (O 2 ) into hydrogen peroxide (H 2 O 2 )

Macfarlane Burnet', Journal of the History of Biology , 47, 147-75.Back Andersson, I, Sjberg, S, Obel, J et al (1971) 'Lymphocyte triggering', in I Lefkovits (2017), The history of the Basel Institute of Immunology .Back Anon, 'Niels K Jerne', American Association of Immunologists.Back Breinl, F, Haurowitz, F (1930) 'Chemische untersuchung des Przipitates aus Hmoglobin und anti-hmoglobin serum und bemerk ungenber die natur der antikorper

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GSH and apoptosis Apoptosis is the canonical form of regulated cell death, characterized by cell shrinkage, chromatin condensation, nuclear fragmentation, and the formation of membrane-enclosed apoptotic bodies 31

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