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In phase 1 and 2 clinical trials, these agents have been shown to increase hemoglobin in both end-stage renal disease and chronic kidney disease patients but not in anephric patients, demonstrating a renal source of the erythropoietin production even in nonfunctioning kidneys

Neurodegenerative Diseases It has been studied for its potential to treat conditions like: Alzheimer's disease: Promoting synaptogenesis (forming new synaptic connections) and protecting neurons may help slow or reverse cognitive decline

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