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Patients diagnosed with diabetes do not produce enough insulin, or their bodies do not use the insulin produced effectively

10 By inhibiting GSK3, the Wnt/beta-catenin pathway is promoted, leading to retinal pigmented epithelium (RPE) formation with specific expression of the RPE marker Otx2

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7 ClinicalTrials.gov LIFT-AD (NCT04488419)Phase 2/3 trial of ATH-1017 (fosgonimeton) in mild-to-moderate Alzheimers disease the clinical test of the HGF/c-Met cognition hypothesis

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However, D+Q has progressed to human clinical trials (several completed) with published efficacy data