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In addition, AML cells overexpressing WT BCAT 1 had lower ROS, and the number of bone marrow markers (CD11b, CD14, CD68, and CD36) that marked cell differentiation on the cell surface was lower, suggesting the involvement of the BCAT 1 CXXC motif in ROS buffering and cell development in AML cells

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This work was supported by grants from the National High Level Hospital Clinical Research Funding (2022-PUMCH-B-010) and National Key Research & Development Plan of China, major project of prevention and treatment for common diseases (2022YFC2505300, subproject: 2022YFC2505304)