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Furthermore, impaired clearance of apoptotic cells leads to the secretion of anti-nuclear antibodies from auto-reactive B cells

& Ando, H

Although many studies reveal associations between platelet biomarkers and ASD, there is an important knowledge gap in linking these markers with ASD and explaining the altered platelet phenotypes detected in ASD patients [406]

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None of these studies however specifically encompasses the domain of brain cancer therefore the huge gap in translational studies of Nrf2 modulators on brain cancer is evident, even though the opportunity for exploration is heavily backed by pre-clinical findings

References: Dumbell, R