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doi: 10.1016/j.parkreldis.2016.08.019 252 LiuJLvXYeTZhaoMChenZZhangYet al

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Physiological Model for Tissue Glutathione Depletion and Increased Resynthesis after Ethylene Dichloride Exposure. The Journal of Pharmacology and Experimental Therapeutics 245 (2): 56368

This is a scenario which overstresses the remaining beta cells, which are still capable of providing insulin in the diabetic metabolic state and thus gives rise also to more misfolded proinsulin (Lenzen 2017)

102 This is done by reducing IL-6, inhibiting B cell, T cell, and Natural Killer (NK) cell activation, as well as decreasing M1 and enhancing M2 activation

The results will provide evidence that will help select doses and forms of Se to administer in clinical trials while according to impact on the glycemic control while elucidating mechanisms of Se metabolism