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Mass cytometry: single cells

Abbreviations CAT: Catalase 3D: Three-dimensional DFUs: Diabetic foot ulcers ECM: Extracellular matrix GOx: Glucose oxidase GSH: Glutathione H 2 O 2 : Hydrogen peroxide HIF-1: Hypoxia-inducible factor-1 IL: Interleukin MMPs: Matrix metalloproteinases NPs: Nanoparticles NSs: Nanosheets O 2 : Oxygen OH: Hydroxyl radicals PB: Prussian blue PDA: Polydopamine PTT: Photothermal therapy POD: Peroxidase PVA: Polyvinyl alcohol ROS: Reactive oxygen species SOD: Superoxide dismutase TNF: Tumor necrosis factor VEGF: Vascular endothelial growth factor References Pea OA, Martin P

Vincristine Despite widespread use of vincristine for the treatment of pediatric cancers including acute lymphoblastic leukemia, sarcoma, medulloblastoma and neuroblastoma as well as a range of tumors in adults, the epidemiology of vincristine-induced peripheral neuropathy (VIPN) is relatively poorly defined

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In women with ICP, BAs levels above 40 mol/L are associated with neonatal mortality, preterm birth, and foetal stress

Cholesterol enriched in the tumor microenvironment induces immune checkpoint expression and CD8 + T cell exhaustion by increasing endoplasmic reticulum stress in CD8 + T cells (333)