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Interacciones de nutrientes Junto con varias vitaminas B (es decir, folato, vitamina B 12 , vitamina B 6 , y riboflavina), la colina es necesaria para el metabolismo de los cidos nucleicos y aminocidos, y para la generacin del donante universal del grupo metilo, la S-adenosilmetionina (SAM) (ver Figura 4 )

Selenium Selenium is an integral part of the enzyme glutathione peroxidase, which plays a major role in cellular antioxidant defense (Higdon 2007b)

CD38 inhibition by apigenin ameliorates mitochondrial oxidative stress through restoration of the intracellular NAD + /NADH ratio and Sirt3 activity in renal tubular cells in diabetic rats