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doi:10.1111/cns.13207

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Allergic Reactions (Rare): Although rare, some individuals can have an allergic reaction to the injection, ranging from a rash or itching to more severe symptoms like swelling of the face, tongue, or throat, dizziness, or difficulty breathing

Passage of bile acids through the enterocyte activates FXR, which promotes the synthesis of fibroblast growth factor 19 (FGF19), which also circulates through the portal vein to the liver where it activates fibroblast growth factor-receptor 4 resulting in inhibition of bile acid synthesis

AOD-9604 does not appear to affect insulin sensitivity or blood sugar, which is one of its key advantages over full-length hGH therapy

6,10,11 Surgical management can be considered if nonsurgical treatment is unsuccessful or the patient has rapidly progressive neurologic symptoms