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doi: 10.1016/j.jaad.2014.03.017 44 KruegerJGBowcockA

In hAPOC3 transgenic mice, RONA-APOC3 significantly reduced serum APOC3 protein by up to 95.2% and lowered TG by 94.1% in parallel following a single subcutaneous injection at 3 mg/kg

PMID: 35011559

Antibodies to intrinsic factor (IF) bind to IF and prevent formation of the IF-B 12 complex, further inhibiting vitamin B 12 absorption

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You don't get everything in your diet, and to kind of cover up for those dietary deficiencies, you need to have supplementation, She says