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Care should be taken to avoid accidental exposure to the drug, and proper protective measures should be employed during administration

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A 2017 review summarised neuroprotective properties of silymarin in animal models, including: Reduction of amyloidogenic activity (relevant in Alzheimer's research) Anti-inflammatory action in nerve tissue Reduction of oxidative stress in the brain Possible positive effects on cognitive function Possible reduction of stroke risk Whether these effects can be achieved in humans at attainable concentrations of silymarin in particular whether sufficient quantities can cross the blood-brain barrier remains unclear

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These cells must sustain lipid production even under metabolically unfavorable conditions like starvation, due to high turnover of surfactant phospholipids in the lung [20]