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By modifying functional groups on their surfaces, polysaccharide-based nanocarriers can be engineered to encapsulate drugs, achieve sustained release, and selectively target specific gut microbial populations (177)

An amide is an amine where one of the nitrogen substituents is an acyl group

Tumor heterogeneity further complicates this landscape, as the extent of GSH dependency varies across tumor types, metabolic states, and microenvironments, with poorly defined consequences for therapeutic response

Key glands affected include the thyroid, which regulates metabolic rate, the adrenals, which manage stress and energy, and the gonads, which are responsible for reproduction and sex hormones

[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Thigpen AE, Davis DL, Gautier T, Imperato-McGinley J, Russell DW

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