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doi: 10.3390/IJMS20020273 68 BayanboldKSinghaniaMFathMASearbyCCStolwijkJMHenrichJBet al

Geroscience 47:611630

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Therapeutic approaches that counterbalance this axis by improving resolution pathways, restoring immunological tolerance, and lowering peripheral inflammatory inputs are the most promising avenues for preventing or delaying neurodegeneration [137]

Ongoing studies explore its influence on cellular communication pathways associated with nutrient utilization, energy balance, and metabolic adaptation