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Such inter-individual variability contributes to unequal therapeutic efficacy, adverse drug reactions, and disparities in virologic suppression, particularly in genetically diverse populations [3]

These microscopic spheres, composed of a lipid bilayer, can encapsulate a variety of compounds, including vitamins, antioxidants, peptides, and other beneficial agents [1]

Erastin induces ferroptosis in tumor cells and enhances the therapeutic ability of conventional antitumor drugs such as doxorubicin and cisplatin [116, 117]

By modulating key proteins involved in these processes, such as cyclins, Caspases, death receptors, and metastasis-related proteins, both compounds significantly suppress tumor growth and metastasis across a range of cancer types

On the contrary, a study by Nimptsch et al

doi: 10.1038/nature20587 53 ImJ