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Protective and therapeutic effects of Scutellaria baicalensis and its main active ingredients baicalin and baicalein against natural toxicities and physical hazards: a review of mechanisms

However, treatments with GABA, DSIP-CBBBP, and DSIP all resulted in increased struggle times compared to the model group, with CBBBP alone not showing a similar effect, indicating a differential impact on depressive-like behaviors and highlighting the potential therapeutic value of these treatments in addressing depressive symptoms associated with insomnia (Riemann et al., 2020

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Inhibition of OCT2 protein by cimetidine prevents cisplatin-induced nephrotoxicity and ototoxicity and they showed that OCT2 is expressed in the hair cells of the cochlea for the first time in the study (Wakai et al., 2022)

Modulation of glutathione and its related enzymes in plants' responses to toxic metals and metalloidsa review