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Alteration of the methylation status of tumor-promoting genes decreases prostate cancer cell invasiveness and tumorigenesis in vitro and in vivo

First demonstration that Trithorax and Polycomb genes have opposing effects on Hox gene expression

Lithium and valproate exert neurotrophic effects that are blockable by specific inhibitors, whereas carbamazepine and lamotrigine are not affected by the same inhibitors

This personalized immunotherapy has the potential to enhance the efficacy of treatment while minimizing off-target effects, leading to more targeted and effective cancer therapies [104, 531, 581, 591]

Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles