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At maintenance, the effect is usually steadier and milder than the first-week change

Rhythms 33 (1), 7683

Mitochondrial damage induced by conditions of oxidative stress

Pros of Calcite Neutralization Less expensive then alternative methods Simple maintenance - usually once per year Non - Electric (Upflow Only) Cons of Calcite Neutralization Increases hardness of water Limited pH control (cannot tune system) Requires addition of water softener Requires post-filter for calcite fines Option 2: Sodium Carbonate (Soda Ash) Another way to get carbonate into the water is to use sodium carbonate, called soda ash

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Take the ketogenic diet and caloric restriction as examples