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It has been observed using in vitro cell culture studies that the nascent amyloid is nontoxic but aged amyloid becomes toxic to neurons [110]

Suggestive evidence that pelvic endometriosis is a progressive disease, whereas deeply infiltrating endometriosis is associated with pelvic pain

Although this review provides a comprehensive analysis of the existing literature on the topic, there are several limitations that must be acknowledged

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A lookback period of no less than 12 months and no longer than 15 months prior to posting the MRF, as described in more detail earlier in this section, provides for a more consistent lookback period across hospitals than a static 12-month lookback period, which we believe helps to alleviate commenters' concerns about having varying amounts of data from which to encode the allowed amounts for an item or service and the complexity of a segmented lookback period if a contract changes midyear

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