This Expert Recommendation article pinpoints key issues associated with identifying the physiological roles of oxidants, focusing on H 2 O 2 and O 2 .
However, in pathological settings, many studies have demonstrated that NOX4 overexpression in tenocytes results in increased expression of matrix MMPs and pro-inflammatory cytokines, including IL-6 and MCP-1, both of which are implicated in tendon fibrosis and degeneration (Mukohara et al., 2021)
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J Dis Med Plants
MSc/PhD Thesis, Department of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, WI, USA
Lou et al
