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Kapust, R.B

Suchandan Sikder, James Cook University, Australia Updates Copyright 2023 Zhu, Liu, Yan, Wang and Pan

demonstrated that a single low-dose immunization with any of the three developed LNP-based herpes simplex virus type 1 glycoprotein D (gDE7) mRNA vaccines (self-amplifying mRNA, unmodified mRNA, and nucleoside-modified non-replicating mRNA vaccines) resulted in the activation of E7-specific CD8 + T cells, generated memory T cell responses to prevent tumor relapses, and destroyed cervical tumors (Ramos da Silva et al., 2023a)

Statistical significance was determined by multiple two-tailed unpaired t -tests with correction for multiple comparisons using the Holm-dk method

Statistical analysis The number of case groups with MTHFR genotypes ( CC, CT, and TT genotypes) and the number of controls were extracted from our pooled studies