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doi: 10.1016/j.tins.2003.08.008 99 ForsbergDRingstedtTHerleniusE

Mutations in KEAP1 are classified as loss-of-function mutations and are distributed throughout the entire KEAP1 genome, with particular enrichment observed within the Kelch domain, which interacts with the DLG and ETGE motifs of NRF2 9,35,80